Royce Fullerton: Check out the German pharmacy museum after entering the paid section. It's free (or included in regular admission, depending on how you look at it).
WorldSoccerShop: The home stadion of Bundesliga club TSG 1899 Hoffenheim is located in Sinsheim and is able to hold almost as many people (30,164) as the city has inhabitants (35,000).
Lisa Young In: One of my favorite bars in Mannheim and also the one that I visit the most! On Mondays they regularly host acoustic jam sessions! The everyday specials are also great!